A Postdoctoral Associate position is available in Dr. Jerold Chun’s lab at the Sanford Burnham Prebys.  The focus of this position will be on bioinformatic approaches to understanding mosaic neural genomes – RNA and DNA – in single cells of the brain.  The position will be central to several teams in the lab that require bioinformatics and will interface with current bioinformatics personnel. 

Duties and Responsibilities:

• Analyze next generation sequencing (NGS, short-read) and especially third generation sequencing (long-read) datasets (genomic and transcriptomic)
• Fluent in R and Python
• Develop new informatic approaches and pipelines in coordination with other researchers in the lab
• Help to maintain and update existing informatics pipelines and lab Github repository
• Manage and organize large sequencing datasets produced by the lab

Education and/or Experience:

• Ph.D. in Biomedical Sciences field with an emphasis on bioinformatics, Ph.D. in Bioinformatics, or Ph.D. with relevant experience in Bioinformatics
• Mastery of command line operations and Linux/Unix operating environments
• Familiarity with high performance computing cluster-based analysis
• Fluency with coding in python, R, and similar languages
• Experience customizing pipelines, algorithms, and quality control metrics for data analysis
• Attention to detail with accuracy
• Ability to communicate effectively in English and to work in a fast-paced environment
• Good social skills

Other Knowledge, Skills and/or Abilities:

• Knowledge of next generation sequencing toolsets (fastqc, STAR, bwa, samtools, GATK, etc.)
• Familiarity with NCBI, UCSC Genome browser, Integrated Genomics Viewer
• Experience with long-read sequencing (Pacific Biosciences and Oxford Nanopore Technologies) and analysis

Experience with single-cell sequencing (10x Genomics) and analysis