Job posting number: #7070425 (Ref:JAX27997)
Posted: September 30, 2020
Application Deadline: Open Until Filled
The Carter Lab has an opening for a postdoctoral associate in the computational biology of Alzheimer’s disease. This position is part of an NIH-funded TREAT-AD center, in which our lab plays a leading role in bioinformatics analysis.
The goal of the TREAT-AD consortium (www.treatad.org) is to translate molecular signatures of late-onset Alzheimer’s disease into new treatments. This process encompasses a range of computational and systems biology approaches, including big data analysis through dimensional reduction, inference of disease origin and progression, integration of multiple annotation and data streams to formulate testable hypotheses, and refinement of hypotheses upon collection of additional data. Our collaborative, multi-institutional group is embedded in a large community of researchers focused on data science and stewardship, structural biology, medicinal chemistry, and the neuroscience of disease. The TREAT-AD center is in turn a part of a major open science initiative to understand and treat Alzheimer’s disease that includes the AMP-AD, ADNI, ADSP, and MODEL-AD research consortia. The Carter Lab also has a leading role in MODEL-AD, in which we create new mouse models of late-onset AD for basic research and preclinical testing.
We are especially interested in candidates with systems biology expertise in model organisms who are seeking to apply their innovative ideas in a translational setting. The structure of TREAT-AD enables collaborative follow-up experimentation and refinement of computational hypotheses. We are dedicated to open science and establishing an inclusive culture to expand our vision of scientific progress.
The Jackson Laboratory provides excellent educational and training opportunities for postdoctoral associates. Exceptional candidates are encouraged to apply for the prestigious JAX Scholar award, which supports promising early-career postdoctoral associates conducting cutting edge biomedical and basic biological research at JAX. The award includes an independent research and travel budget and a salary above our standard postdoctoral scale (https://www.jax.org/education-and-learning/pre-and-postdoctoral-program/jax-scholars
To apply, please submit 1) a cover letter outlining research accomplishments and interests, 2) a current CV, and 3) names and contact information for three references.
The successful candidate will perform independent computational analyses of multiple data sets to prioritize molecular hypotheses of Alzheimer’s disease development. They will document and report results to center colleagues for collaborative experimental validation. They will lead efforts to disseminate research results including all data and analysis via publications, data sharing, and presentations to consortium peers and at scientific meetings. Postdocs are also expected to participate in the broader Jackson Laboratory community to foster their career development and progression.
• Ph.D. in bioinformatics, computational biology, biostatistics, or related field is required;
• Exceptional verbal and written communication skills;
• Demonstrates ability to be collaborative across disciplines; and
• Demonstrated writing ability as evidenced by significant contribution/leadership role in bringing a minimum of one 1st author paper from graduate work to publication.
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY - Courage and commitment to do what is right
PEOPLE - Inspiring our people to enhance the health of all
ONE TEAM - Unified by our promise to transform medicine and science
EXCELLENCE - Achieving world-class results
INNOVATION - Leading with discovery and creative solutions
STEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program, an onsite full service cafeteria, and a fully operational primary care facility available to employees and their families.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
Employment will require successful completion of references, background check, credit check, pre-employment physical, and an appropriate non-compete agreement.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about career opportunities at JAX: http://www.jax.org/careers.