Clinical Bioinformatics Analyst
Job posting number: #7071320 (Ref:JAX28066)
Posted: October 23, 2020
Application Deadline: Open Until Filled
The Clinical Bioinformatics Analyst is responsible for oversight and day-to-day operations of bioinformatics data in the CLIA laboratory. This position is responsible for evaluating, validating, implementing and supporting new bioinformatics analysis pipelines, testing/validation scripts, and other tools required for clinical genomic testing. This position also requires administrative duties such as laboratory reports, management of quality metrics, and regular personnel meetings. This position will coordinate with other departmental scientists, supervisors, managers within the Clinical Genomics Laboratory to implement policies and procedures that achieve the strategic goals set by the Clinical Laboratory Director.
- Oversee the operations of the clinical genomic data from Molecular Laboratory.
- Successfully sustain CLIA/CAP certification, including competency and proficiency assessments, for molecular diagnostics laboratory.
- Drive continuous improvement of data analysis tools and methods used for assay design. Experience in building automate pipelines for data analysis to drive continuous improvement.
- Ability to analyze and interpret high-throughput clinical genomic data generated by microarray, next-generation sequencing, qPCR, ddPCR, others.
- Ability to evaluate available literature and other public and private data sources including but not limited to dbSNP, ExAC, gnomAD, ClinVar, IGV, UCSC genome browser, cBioPortal, TCGA, NCBI, Ensembl, Broad FireHose.
- Work with IT to ensure (1) data integrity and security, and (2) data is backed up in long term storage database maintenance.
- Design data analysis projects plans and timelines and maintains the appropriate documentation.
- Works both independently and collaboratively, and comfortable handling several concurrent, fast-paced projects.
- MS or PhD in Genetics, Biochemistry, Molecular Biology, Bioinformatics or related biological field required.
- MS level will have at least 6 years of experience. PhD will have at least 3 years of experience.
- Strong experience in the use of a high-level programming language such as R or Python for complex data analysis.
- Extensive experience in different aspects of genomics, including an excellent understanding of sequence data and its applications.
- Demonstrated knowledge and experience in sequencing based molecular approaches and sequencing based interrogation.
- Extensive experience in protocol development and optimization procedures with effective problem-solving and decision-making skills.
- Strong working knowledge of quality assurance practices and procedures.
- Leadership experience sufficient to effectively hire, train, coach, and performance manage employees.
- Demonstrated ability to conduct and perform collaborative research and experience in the preparation and handling of clinical reports.
- Excellent interpersonal, verbal, and written communication skills; strong organizational and analytical skills; and the ability to work independently as well as in a highly cooperative team environment.
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,200 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center, a genomic medicine institute in Farmington, Conn., and facilities in Ellsworth, Maine, Sacramento, Calif., and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.
JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.
In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY - Courage and commitment to do what is right
PEOPLE - Inspiring our people to enhance the health of all
ONE TEAM - Unified by our promise to transform medicine and science
EXCELLENCE - Achieving world-class results
INNOVATION - Leading with discovery and creative solutions
STEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program and an onsite full service cafeteria.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about career opportunities at JAX: http://www.jax.org/careers.