In Vivo Services Research Associate
Job posting number: #7072622 (Ref:JAX28134)
Posted: November 27, 2020
Application Deadline: Open Until Filled
Under the general supervision of an Scientist/Senior Scientist, the incumbent is responsible for generation and validation of humanized mice, maintenance of PDX models (for both solid and liquid tumors), maintaining accurate inventory, conducting a variety of product development research efforts including optimizing assays to monitor functions in humanized mice, engraftment kinetics, and drug response. Makes detailed observations, analyzes data and interprets results. Keeps excellent data records and easy retrieval to fulfill data requests. Ensures the experimental protocols are compliant with animal welfare and are faithfully transferred to the Operation team for consistency in product offerings. Individual Research Associates will be a collaborative member of the cross functional In Vivo department and are assigned to work within the Operations team for laboratory management activities. The incumbent ensures prompt communication with the team members, a successful transfer of studies into the lab and the execution of studies with the highest quality and with scientific integrity. In addition, the incumbent is responsible for ensuring the accuracy of data entries AXAPTA and LIMS entries.
- Contributes to the technical design of experiments and methods, develops conclusions, and makes recommendations for further action. This includes designing novel methodology for solving tactical problems and improving experimental procedures through discussion with internal and external investigators.
Conducts varied and complex experiments requiring high-level technical skills without deviations. Anticipates challenges, troubleshoots common technical issues,and plan for alternatives. This includes performing complex laboratory techniques such as cell culture, flow cytometry, tumor biology, and standard cellular and in vivo pharmacology experiments with a significant amount of independence. Collects and analyzes data and interprets results.
Prepares detailed written and oral presentations of data, results, and conclusions. Maintains laboratory notebook and electronic LIMS data. Documents experimental results and procedures clearly and concisely in required format.
Work with the Operations department to coordinate various lab management tasks. This includes, but is not limited to, supply ordering, inventory management, coordinating sample shipments, and tracking equipment repairs and calibrations.
Ensures appropriate IACUC, IRB, IBC protocols and/or amendments are in placeand are accurate relative to the experimental design.
Ensures the experimental protocols are faithfully transferred to the Operations or In Vivo Services team for consistency in product offerings.
- Bachelor’s degree with at least 5 years of relevant work experience within an advanced biosciences research laboratory or a Master’s degree with at least 3 years of relevant work experience within an advanced biosciences research laboratory.
- Must be knowledgeable in advanced cell culture techniques, cell isolation and characterization techniques; flow cytometry techniques and flow data analysis.
Excellent interpersonal skills to execute tasks in a collaborative environment. Must be able to establish two-way communication with collaborators, technicians, scientists and department heads regarding specific needs and deadlines.
- Strong proficiency with a variety of software tools including Microsoft Office, GraphPad, and FlowJo.
Exceptional problem solving skills and ability to resolve technical issues independently and in a timely manner. Excellent organizational and time management skills and the ability to pay attention to detail while multi-tasking in a fast paced work environment.
Exceptional problem-solving skills and ability to resolve technical issues independently and in a timely manner.
Excellent organizational and time management skills and the ability to pay attention to detail whilemulti-tasking in a fast-paced work environment.
The Jackson Laboratory (JAX, www.jax.org) is a nonprofit biomedical research institute with over 2,000 employees whose mission is to discover precise genomic solutions for human disease and empower the global biomedical community in the shared quest to improve human health. A National Cancer Institute-designated Cancer Center, JAX has a mammalian genetics headquarters in Bar Harbor, Maine, a facility in Sacramento, California, and a genomic medicine facility, The Jackson Laboratory for Genomic Medicine (JAX-GM), in Farmington, Connecticut.
The JAX® Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California. Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County. Sacramento is the birthplace of the nation’s Farm to Fork movement, and offers excellent restaurants, gastro-pubs, wineries, theaters, and museums. Outdoor activities are plentiful: Boating, white water rafting, and riding the scenic bicycle trails are popular. Housing and other costs of living are more affordable in Sacramento and its surrounding suburbs than in most other neighboring areas in the North Bay, making Sacramento one of the hottest housing markets in the country year after year.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
INTEGRITY - Courage and commitment to do what is right
PEOPLE - Inspiring our people to enhance the health of all
ONE TEAM - Unified by our promise to transform medicine and science
EXCELLENCE - Achieving world-class results
INNOVATION - Leading with discovery and creative solutions
STEWARDSHIP - Caring for and enhancing the resources entrusted to us
What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries and a comprehensive benefits package including a medical plan, outstanding retirement plan, generous paid time off and tuition reimbursement.
Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.
Employment will require successful completion of references, background check, pre-employment physical, and drug test.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
Learn more about at opportunities at JAX at http://www.jax.org/careers