Computational Scientist (Associate/Full/Senior)

The Jackson Laboratory for Genomic Medicine

Farmington, CT

Job posting number: #7087576

Posted: October 21, 2021

Job Description

Summary
The Genome Technologies department is seeking an experienced Computational Scientist to join their team. Under minimal supervision of the Director of the Genome Technologies, the Computational Scientist will participate in the 3D chromatin biology and technology development program, make contributions to develop cutting-edge technologies for comprehensive mapping of 3D genome organizations in human and mouse, and uncover the molecular mechanisms that control important genome functional modulation including gene transcription regulation. They will participate in projects, developing and optimizing computational approaches as well as analysis strategies for omics data analysis and interpretation for a wide scale of clinical and biomedical applications.

The Computational Scientist exercises independent judgment in determining methods and approaches for data integration across various technology platforms and data types, establishes and maintains analysis standards, sets priorities, and proactively plans for the proper operation of analysis software and also improves existing data analysis tools and implements new tools for general use. They will also play a significant role in defining the biological significance of the data and its interpretation and contribute to the writing for publications and grant applications on new sequencing approaches.

The role will involve significant interaction and collaboration with the research teams within The JAX campuses and external collaborators. This position offers great growth opportunity to contribute both in novel technology development and advanced genomic discoveries that have immediate relevance in genetics and clinical significance in an innovative and fast-paced team environment.


Successful candidates will have:

Strong coding abilities in R and Python
In-depth knowledge and experience in High throughput sequence data analysis (ChIP-seq, RNA-seq, ATAC-seq, Hi-C/ChIA-PET).
Extensive knowledge in probability theory, biostatistics and proven track record of “omics” data analysis.
Candidates who can perform independent collaborative work and leading contributions to a biological discipline would be preferred.
Responsibilities
Associate/Full/Senior Computational Scientist carries out Computational analysis of omics data, algorithm implementation as well as bioinformatics programming and expert reasoning and leadership for the projects. Evaluates data, for quality assurance and mining bioinformatics databases and contributes to the presentation of the results at conferences, workshops, and contributes to the preparation of manuscripts.
Associate/Full/Senior Computational Scientist participates in departmental and project activities such as developing pipelines, participating in conducting courses and workshops at JAX, provide leading contributions to grant applications, mentoring students and scientists, and presenting results & processes to JAX community and at conferences and workshops as assigned.
Associate Computational Scientist starts demonstrating strong potential to develop analytical expertise to a few selected biological disciplines, independent collaboration and project leadership.
Full/Senior Computational Scientist independently establishes collaborations within The Jackson Laboratory provide expert reasoning to the projects relevant to the scientist’s disciplines of research, lead or co-lead grant writing consistently in collaboration with the researchers at The JAX as demonstrated by role as PI and co-I in the grant applications. A scientist also demonstrates strong potential to carrying out the collaborative bioinformatics program independently.
Senior Computational Scientists are expected to independently establish collaborations within The Jackson Laboratory, provide expert reasoning to the projects relevant to the disciplines; contribute to grant writing in conjunction with the researchers at JAX. A senior scientist also demonstrates strong potential to carrying out the collaborative bioinformatics program independently. Mentor junior scientists, secure funds for the scientist’s group through independent collaborative research program and assist their manager in policy making.
Qualifications
PhD in Bioinformatics, Computer Science, Biostatistics or any relevant area required for all levels. The candidates who are near the completion of their PhD can also apply.
Associate Level: Possess 2-5 years of experience in Bioinformatics research, excluding time spent to obtain PhD.
Full level: Possess 5-10 years of experience in Bioinformatics research, excluding time spent to obtain PhD.
Senior Level: Possess 7-12 years of experience in Bioinformatics research, excluding time spent to obtain PhD. Candidates with significant pre-doctoral experience in the relevant research area as a researcher and demonstrated research track record during the pre-doctoral period will also be considered.
Successful incumbents demonstrate excellent verbal and written communication skills.
Demonstrated experience managing projects and collaborations.
Prior successes in and desire to contribute to team projects on an ongoing basis is a must.
Demonstrated ability to establish research and mentoring leadership in addition to lead obtaining grant funds to support part of the group led by the Senior Computational Scientist.
Senior Computational Scientists are expected to sustain collaborations with The JAX research staff and faculty on both the Farmington, CT and Bar Harbor, ME campuses and to visit the other sites of JAX on a regular basis and as required.
The candidates with proven track record of “omics” data analysis, statistical genetics & Biostatistics, independent collaborative work and leading contributions to a biological discipline would be preferred.
About JAX:

The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.


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