Postdoctoral Fellow – Testing Gene Editing Therapies Against Viral Infection in a Human Lung-on-a-Chip

The Wyss Institute for Biologically Inspired Engineering at Harvard University

Boston, MA

Job posting number: #7108353

Posted: August 18, 2022

Application Deadline: Open Until Filled

Job Description

About the Wyss:

The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances.

Role Description:

Imaris Snapshot
The Wyss Institute for Biologically Inspired Engineering at Harvard University seeks outstanding postdoctoral applicants with expertise and knowledge of virology and lung biology to join an interdisciplinary team of biologists and engineers for the development of novel in vitro human organ-on-chip microsystems technologies to study and model respiratory viral infection and propagation in vitro.

In This Role You Will Have:

Strong interest in contributing to multidisciplinary teams (engineers, biologists/physiologists, clinicians) is critical for this position
Expertise in working with influenza and/or corona virus, in vitro culture, inflammatory responses, and characterization of cells derived from the lung (small airway/alveolus), as well as knowledge of gene editing techniques, flow cytometry, basic molecular and cell biology concepts and techniques is a must.

Expertise in respiratory viral infection and gene editing therapies, as well as lung biology, function, and inflammatory responses, with an interest in applying this expertise in combination with modern bioengineering practices by leveraging Human Organ-on-a-Chip technology in vitro
This postdoctoral fellow is expected to develop and lead an interdisciplinary research project aimed at using microengineered organ-on-chip models, to simulate respiratory viral infection, and exploring their use in drug discovery applications.
What You’ll Need:

Ph.D. and/or M.D.
Proven record of high-quality publications in the field of viral infection and/or lung biology or physiology
Previous experience in gene editing technologies of the lung, such as CRISPR is a plus.
Benefits and Perks:

Medical/Dental/Vision: We offer a variety of excellent medical, dental, & vision plans. All coverage begins as of your start date.
Time Off: 20 days of vacation per year
Tuition Assistance Program: Competitive tuition assistance program, classes at the Harvard Extension School and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness Options: Harvard offers programs and classes at little or no cost, including stress management, nutrition, meditation, and complimentary health services.
Where You Can Apply:

Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to [email protected] using the subject line “LUNG VIRUS INFECTION ON CHIP- POSTDOCTORAL FELLOW APPLICATION.”

Working Conditions

Harvard requires COVID vaccination for all Harvard community members. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement, exemptions, and verification of vaccination status may be found at the University’s “COVID-19 Vaccine Information” webpage:

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Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law. Demonstrates a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.

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