Postdoctoral Scientist – Metastatic Niche, KS Chan lab

Cedars-Sinai Medical Center

Los Angeles, CA

Job posting number: #7108474 (Ref: HRC0937639)

Posted: August 19, 2022

Application Deadline: Open Until Filled

Job Description

Grow your career at Cedars-Sinai!

Cedars-Sinai is a nonprofit academic healthcare organization serving the diverse Los Angeles community and beyond. We are one of the leading institutes for competitive research funding from the National Institutes of Health. As an international leader in biomedical research, we translate discoveries into successful treatments with global impact. Cedars-Sinai is a hub for biomedical research with discoveries occurring in 26 departments and institutes that encompass the full spectrum of medicine.

Dr. Keith Syson Chan’s laboratory is seeking multiple postdoctoral scientists to join their dynamic team in sunny California! Syson Chan lab is comprised of an interdisciplinary team ( focusing on cancer research that can be translated into early-phase clinical trials or biomarkers to impact patients. We integrate innovative single-cell technologies and various study models (e.g., patient-derived xenografts, syngeneic murine models, GEMM) to address key research questions spanning

To characterize a newly discovered metastatic niche [Nature Communications 10: 2131 (2019) and Nature Reviews Urology 2022] its interaction with other myeloid cells in the microenvironment to modulate metastatic lung colonization. This project builds on existing RNA seq profiling of tumor and niche cells from human patients and mouse models, with established in vivo metastatic patient-derived xenograft and syngeneic models, accessibility to state-of-the-art multiplex imaging and microfluidic systems to recreate 3D microenvironment in vitro, and other organoid models for investigating mechanism-based therapies. An ideal applicant will be have expertise in the metastatic cascade or tumor microenvironment, familiar with techniques e.g., FACS, 2D/3D culturing systems, interests in the collagen scaffold/mechanobiology or molecular biology is highly preferred.

To learn more:

Primary Duties and Responsibilities:

  • The design of research directions and experiments in cooperation with the mentor. Will keep appropriate experimental records and analyze the results with the PI.
  • Explore literatures and state-of-the-art techniques relevant to the project.
  • Compiling figures and text for the submission of publications and presentations as primary author or co-author.
  • Highly encouraged to apply for fellowship or career transition grant application for career advancement.

Essential Job Responsibilities:

  • Participate and present at lab meetings, research-oriented interest groups, and attend departmental or cancer center seminar series


  • Doctorate (MD, PhD, VMD, or DDS) in biomedical sciences, cancer biology or immunology.


Working Title:Postdoctoral Scientist – Metastatic Niche, KS Chan lab
Department:Home Dept - Hem - Onc
Business Entity:Academic / Research
Job Category:,Academic/Research,Academic/Research
Job Specialty:Postdoctoral
Position Type:Full-time
Shift Length:8 hour shift
Shift Type:Day

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at [email protected] and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy.

Apply Now

Please mention to the employer that you saw this ad on