Bioinformatics Scientist/Specialist Shared Resource

Sanford Burnham Prebys Medical Discovery Institute

San Diego, CA

Job posting number: #7111121 (Ref:spd-2178519)

Posted: September 20, 2022

Application Deadline: Open Until Filled

Job Description

SBP is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease, and advancing scientific discoveries to profoundly impact human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology, and children’s diseases, and is anchored by our NCI-designated Cancer Center and advanced drug discovery capabilities.

The Bioinformatics Shared Resource role provides cutting-edge computational and systems biology support to the Institute and its NCI-designated Cancer Center. We specialize in omics data analysis, multi-omics data integration, network and pathway analysis. Different levels of data analyses are provided, based on the complexity of researchers’ data sets. This may include automated pipeline-based analyses, customized deep data mining, and hypothesis driven in-silico drug discovery. We are looking for a talented candidate for a Bioinformatics Scientist (applicants with a Ph.D.) or Bioinformatics Specialist (applicants with MS or BS) position in this challenging computational team. The successful candidate should have strong genomics, computational, and statistical skills, great communication and interpersonal skills, and able to independently solve scientific projects.

Primary Responsibilities

  • Analyze, interpret and integrate comprehensive, state-of-the-art omics data sets, including Next Generation Sequencing (NGS) datasets (such as RNA-seq, ATAC-seq, ChIP-seq, Exome-seq, DNA-seq), single cell datasets (scRNA-seq, scATAC-seq), spatial omics (such as Nanostring DSP), and proteomics datasets.
  • Implement analysis pipelines and customize tools for omics data analysis, including scripting, programming, statistical analyses and applying common standard analysis tools and algorithms (e.g., R/Bioconductor, Python).
  • Independently support and manage multiple parallel projects from the institute and cancer center, and contribute to the general technical knowledge of researchers.

Required Experience

  • Ph.D. in Bioinformatics, Biostatistics, or Life Sciences or equivalent studies for Bioinformatics Scientist position. MS or BS with equivalent training and work experience for Bioinformatics Specialist.

Required Knowledge, Skills and/or Abilities

  • Ability to use current bioinformatics tools and have an in-depth knowledge of advanced sequencing, array-based technologies, and proteomics technologies
  • Proficiency in NGS data analysis
  • Strong programming skills including Perl/Python and R/Bioconductor
  • Experience with Linux/Unix operating system
  • Solid understanding of statistics
  • Sufficient knowledge of biology to effectively contribute to investigators’ projects
  • Communicates effectively and collaborates well with Principal Investigators and their team members
  • Work independently as well as in a team environment
  • Possess strong attention to detail, analytical, time management, organizational, communication, and interpersonal skills
  • Embody the Institute’s core values of Commitment, Collaboration, Communication, Community and Compassion

Desired skills

  • Experience with bioinformatics workflow manager (e.g. Nexflow and/or Snakemake)
  • Experience with version control systems (e.g., GitHub, Gitlab)

Sanford Burnham Prebys is an Equal Opportunity employer – M/F/Veteran/Disability – committed to the hiring, advancement and fair treatment of all individuals. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law. For additional information about your rights as an applicant, click HERE.

 





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