Research Associate II - Immune Monitoring in Preclinical and Clinical Vaccine Studies

City of Hope

Duarte, CA

Job posting number: #7114107 (Ref:10018923)

Posted: November 22, 2022

Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes, and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution.  AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope’s specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope’s commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities.  Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve to build trust and understanding.  We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

The Diamond lab has an exciting opportunity for a motivated Research Associate II scientist with an interest in immune monitoring in preclinical and clinical vaccine studies.  The successful candidate will join a team committed to immunologically evaluate experimental vaccines for SARS-CoV-2, the virus that causes COVID-19, and for cytomegalovirus (CMV), which is a major viral complication after bone marrow or solid organ transplant and in pregnant women. Both vaccines have been developed at City of Hope by the Diamond group. The position will be jointly mentored by Flavia Chiuppesi, PhD and Don J. Diamond, PhD. 

 

It will be the responsibility of the candidate to conduct immune monitoring in in laboratory animals undergoing preclinical studies and in patients/volunteers who are enrolled in the clinical trials. In vitro immunoassays, including but not limited to ELISA and neutralization assays, will be used to analyze vaccine and viral responses.

 

Candidates should have a strong background in viral immunology, with documented experience in developing and performing immunoassays using serum samples. Experience in cell culture, data analysis software, and high throughput immunoassays is a plus. 

Basic education, experience and skills required for consideration:

  • Bachelors degree in Molecular Biology, Cell Biology, Microbiology or other related field with 2 years of experience or Masters with 1 year of experience is required
  • Strong background in immunology, with documented experience in developing and performing immunoassays including ELISA and neutralization assays.
  • Experience in cell culture, data analysis software, and high throughput immunoassays is a plus. 

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

  • For more information on Dr. Don Diamond’s research please visit here

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer.  All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.



City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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