Senior Research Assistant - Neuronal Innervation of Osteoarthritic and Aging Joints

Baylor College of Medicine

Houston, TX

Job posting number: #7116703 (Ref:13887-en_US)

Posted: November 23, 2022

Application Deadline: Open Until Filled

Job Description


The Restoring Joint Health and Function to Reduce Pain (RE-JOIN) consortium is a new NIH-funded initiative that brings scientists from various US-based institutions, including Baylor College of Medicine (BCM), together to better understand the origins of joint pain in diseases such as osteoarthritis. At BCM, the RE-JOIN team consists of five research groups, including the Lee lab, that have joined forces to tackle this research question. To help us characterize how neuronal input into the knee joint changes with age and with disease, we are recruiting a research assistant who has strong work ethics, and has excellent interpersonal and organizational skills. 


The Sr. Research Assistant will work as part of a large, interdisciplinary team, so the successful candidate must have strong communicative and interpersonal skills. Their primary tasks will be to handle the mouse husbandry (mouse breeding, genotyping, and documentation), perform histology, and to assist, or perform, the surgeries to induce osteoarthritis. Depending on the needs of the project, these tasks may expand to also include neuronal mapping assays, such as viral-based retrograde tracing. The Sr. Research Assistant will be trained on specific research techniques within the group.


 For more information about our lab, please visit 

Job Duties

  • Animal husbandry: maintain transgenic mouse colony, perform PCR-based genotyping assays, monitor breeding activities, and keep detailed records in the lab's database. 
  • Assist (or perform) surgeries in mice to induce osteoarthritis and monitor disease progression afterwards.
  • Collect mouse tissues for basic histology on fixed tissues, including tissue sectioning and staining.
  • Perform a broad range of cell, molecular biology and biochemistry assays, including DNA-, RNA-, and protein extraction from cells and tissues, immunohistochemistry, immunofluorescence, western blots, real time PCR, etc. 
  • Maintain careful and detailed documentation of experiments, collected data, and analysis in lab notebooks. This task will require a working knowledge of excel spreadsheets.

Minimum Qualifications

  • Bachelor's degree in a Basic Science or related field. 
  • Four years of relevant experience.

Preferred Qualifications

  • Master's Degree in a basic science or related field.
  • Two to three years of experience working with rodent research models. 
  • Experience with supporting and/or performing rodent surgeries.
  • Experience performing immunostaining and histology.
  • Excellent communication and interpersonal skills.
  • Background in genetics, molecular biology, and neuroscience.



Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.


Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

Apply Now

Please mention to the employer that you saw this ad on

More Info

Job posting number:#7116703 (Ref:13887-en_US)
Application Deadline:Open Until Filled
Employer Location:Baylor College of Medicine
United States
More jobs from this employer
Institution Website