Job Description

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.



What You Will Achieve

Worldwide Research and Development (WRD) at Pfizer combines research and technology units that have deep disease area expertise and cutting-edge science and platforms to discover and develop innovative therapeutic programs in small molecules and biotherapeutics, including vaccines. In your role, you will work closely with other biochemists, medicinal chemists, and biologists and apply your background/skills to understanding the underlying biochemical pathways and characterizing the molecular interactions between chemical compounds and target protein(s).

As an Associate Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. Your strong foundation in general scientific practice, its principles and concepts will help in meeting critical deadlines. You will be relied on as a technical contributor to assess the assigned tasks and make decisions that involve direct application of your knowledge.

It is your hard work and dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.



How You Will Achieve It

Apply technical skills to complete assigned work within own work group/project team.

Perform routine sample testing in support of process development, formulation development, release, stability, and characterization of vaccine candidates.

Implement and develop ultra-high throughput bio-analytical platforms for various chemical, pharmaceutical, and ADME screens.

Learn and deploy analytical methods (especially LC and MS techniques) to identify and validate binders to different type of pharmacological targets, analyze small molecules and support weekly in vitro ADME/pharmacology assays.

Document experiments, analyze data and provide conclusions obtained from assay development and sample testing contemporaneously in either an electronic or paper notebook as directed.

Contribute to, draft, and revise laboratory methods and reports.

Interface with clinical sample submitters and coordinate resources for their study support, where applicable.

Maintain up to date records as required by Pfizer policy and comply with all safety training and good laboratory practices.

Plan daily workflow to complete the tasks/experiments outlined by the supervisor.



ROLE SUMMARY

This individual will be responsible for supporting analytical characterization of viral vaccine strain change activities within the Vaccine Research and Development – Early Bioprocess Development group. The candidate will assist with the analytical team to support the RNA drug substance, LNP drug product, and critical reagent production and characterization to enable strain changes as required. The individual will provide scientific and technical support for the team of analytical scientists, as well as work with multifunctional teams outside of their reporting structure.

ROLE RESPONSIBILITIES

Effectively execute analytical protocols for release and characterization of RNA drug substance, LNP drug product, and critical reagents to support viral vaccine strain change.

Analyze data obtained with minimal supervision.

Document experiments contemporaneously in either an electronic or paper notebook as directed and provide to supervisor or designee for review.

Contribute to authoring technical documents including development reports, analytical test methods, and method qualification reports.

Perform other duties as assigned. This includes maintaining laboratory instruments as necessary according to applicable guidelines and ordering frequently used reagents and materials.

Read scientific and technical literature to stay current in the field and to bring new and improved technologies to the laboratory.

Qualifications

BS degree in biology or related discipline with 0+ year relevant experience.

A strong background in biochemical and immunological techniques is essential.

Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is required.

Strong verbal and written communication skills



Nice-to-Have

Previous experience with developing immunoassays for detecting proteins or glycoconjugates is desired.

Experience with protein purification, cell transfection, Flow Cytometry, and cell culture in a BSL2 environment is a plus.

Experience with documentation of laboratory notebook in an electronic format is desired.

PHYSICAL/MENTAL REQUIREMENTS

Standard laboratory conditions – sitting, standing, primarily lab based

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

40 hours per week.

Work Location Assignment: On Premise

Other Job Details:

Eligible for relocation package

Eligible for employee referral bonus