Research Assistant II Lab

Harvard Medical School

Boston, MA

Job posting number: #7121198 (Ref:hh-60946BR)

Posted: January 15, 2023

Application Deadline: Open Until Filled

Job Description

Position Description
The Brugge lab has a long-standing interest in studying breast cancer using innovative techniques, with the ultimate goal of helping improve treatment strategies for patients.

We are looking for a highly motivated research assistant to join our team. As a Research Assistant II, you will be working on projects that investigate the mechanisms of breast cancer initiation and progression in breast tissues of women at high risk of developing breast cancer. You will be responsible for isolating cells from primary breast tissue for analysis using cutting-edge technologies as well as optimizing organoid cultures from these tissues, under the direct supervision and mentorship of a senior postdoctoral fellow. Former research assistants in the lab have made valuable contributions resulting in co-authorship in high-impact publications and have successfully moved on to MD and/or PhD programs as well as industry positions.

Responsibilities will include:
  • Perform cell dissociation protocols on human breast tissues from donors who are high risk for breast cancer;
  • Perform single cell DNA sequencing experiments to identify single nucleotide variants and copy number alterations in breast epithelial cells;
  • Perform flow cytometry and FACS cell sorting;
  • Cell culture and aseptic technique, working with mice, DNA isolation;
  • Establish and maintain a database of donor samples that contain de-identified clinical information;
  • Assist in organoid culture and optimization of conditions to characterize early stages of tumorigenesis;
  • Assist in the design of laboratory experiments, techniques, and protocols;
  • Perform related laboratory maintenance such as maintaining and cleaning equipment and ordering supplies;
  • Maintain accurate and detailed record of experimental results.
Basic Qualifications
College background or equivalent work experience, preferably in biochemistry, cell biology, or a related discipline 1-2+ years of experience.
Additional Qualifications and Skills
  • Bachelor's or Master's degree preferred;
  • Highly motivated, good work ethic, and able to work independently and as part of a team;
  • Follow protocols with attention to detail;
  • Produce accurate and high-quality work;
  • Think creatively to solve problems;
  • Excellent skills in communication, organization, and time management;
  • Database Management Certificate strongly desired;
  • Seeking a committed team member for 1+ years, depending on performance and funding.
Additional Information
This is a one-year term position from the date of hire, with the possibility of extension, contingent upon work performance and continued funding to support the position. 

Offer contingent upon successful completion of a pre-placement medical evaluation.

This is an in-person position based on our campus in Boston.

The University requires all Harvard community members to be fully vaccinated against COVID-19 and remain up to date with COVID-19 vaccine boosters, as detailed in Harvard’s Vaccine & Booster Requirements. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement, exemptions, and verification of vaccination status may be found at the University’s “COVID-19 Vaccine Information” webpage:

Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.

Harvard University offers an outstanding benefits package including:
  • Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 12.5 paid holidays, and 3 paid personal days per year.
  • Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
  • Retirement: University-funded retirement plan with full vesting after 3 years of service.
  • Tuition Assistance Program: Competitive tuition assistance program, incredibly affordable classes directly at the Harvard Extension School, and discounted options through participating Harvard grad schools.
  • Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
  • Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation, and complementary health services.
  • Harvard access to athletic facilities, libraries, campus events, and many discounts throughout metro Boston.
The Harvard Medical School is not able to provide visa sponsorship for this position.

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Commitment to Equity, Diversity, Inclusion, and Belonging
We are committed to cultivating an inclusive workplace culture of faculty, staff, and students with diverse backgrounds, styles, abilities, and motivations. We appreciate and leverage the capabilities, insights, and ideas of all individuals. Harvard Medical School Mission and Community Values
EEO Statement
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

Harvard Medical School strives to cultivate an environment that promotes inclusiveness and collaboration among students, faculty and staff and to create new avenues for discussion that will advance our shared mission to improve the health of people throughout the world.

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More Info

Job posting number:#7121198 (Ref:hh-60946BR)
Application Deadline:Open Until Filled
Employer Location:Harvard Medical School
United States
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