Job Description

Job Description: Senior Scientist, Biology – Internal Medicine

ROLE SUMMARY

The key strategic focus area within our Cardiovascular Diseases Internal Medicine Research Unit (CVD-IMRU) is identifying novel therapies to prevent or treat Heart and Vascular diseases associated with diabetes or the metabolic syndrome including obesity and renal disease. As a member of our Discovery Biology team, you will be playing a significant role in the drug discovery process including ideation and hypothesis testing, identification and validation of therapeutic targets and disease related biomarkers. You will lead a team of experimental scientists as well as collaborate effectively with a wide spectrum of scientific partners representing diverse disciplines. You will build and facilitate collaborations with partners in the academic scientific community, as well as within the larger Pfizer network. You will have daily interactions with a team of creative and innovative scientists, working collaboratively in a supportive environment to conduct rigorous scientific and drug discovery research.

ROLE RESPONSIBILITIES

• Apply creative thinking and scientific expertise to the formulation of strategies to identify and validate therapeutic targets in key areas of interest to the Internal Medicine Research Unit.
• Maintain an awareness of ‘cutting edge’ scientific and technical developments in preclinical to clinical translation and apply these where possible to advance the portfolio programs.
• Conceptualize, design and conduct experiments.
• Mentor junior Scientists in developing skills essential to the execution of rigorous scientific research
• Organize and conduct in vivo and in vitro studies independently (including experimental design, data collection, interpretation, and presentation).
• Quantify and translate experimental results to advance the understanding of how metabolic pathways and complex physiological systems are altered by diseases and how they respond to therapeutic interventions.
• Build and facilitate collaborations with partners in the academic scientific community, as well as within the Pfizer network of scientists.
• Present research findings to Pfizer colleagues and the scientific community through publication in peer-reviewed journals and talks and posters at scientific meetings.
• Present and represent research programs to Pfizer leadership.
• Ensure that all research/discovery work is conducted with highest quality and ethical guidelines and in accordance with relevant regulatory, QC, and compliance guidelines.

QUALIFICATIONS

• PhD with a minimum of 3 years of research experience in Cardiovascular diseases (Pharma research or Academical Post-Doc experience).
• Experience in iPSC-derived models of cardiomyopathies is required.
• Demonstrated ability to review critically available data and to think creatively in formulating novel hypotheses.
• Successful record of scientific accomplishments as indicated by scientific publications and presentations.
• Deep expertise in cardiac physiology and metabolism and/or signaling pathways.
• Experience performing in vitro, in vivo and ex vivo experiments.
• Experience leading teams and junior Scientists
• Experience working independently as well as with an interdisciplinary team of scientists in a highly collaborative environment.
• Demonstrated ability to contribute to multiple projects in parallel with learning agility and scientific rigor.
• Strong written/verbal communication skills

Relocation assistance may be available based on business needs and/or eligibility.