Senior Associate Scientist - Early Bioprocess Development, Vaccine R&D
Pfizer Inc.
Pearl River, NY
Job posting number: #7145889
Posted: May 18, 2023
Salary / Pay Rate: 62,800.00 - 125,400.00 USD Annual
Application Deadline: June 19, 2023
Job Description
Why Patients Need YouPfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
The Senior Associate Scientist is responsible for supporting the manufacture of materials for viral strain change within the Vaccine Research and Development – Early Bioprocess Development group. The colleague will execute process activities required for the manufacture DNA template, RNA drug substance, LNP drug product, and critical reagents. The responsibilities include UF/DF, affinity chromatography, column packing, and testing and analysis of in-process samples using various bioanalytical methodologies. The colleague will be expected to summarize and evaluate study and purification results. Detailed and accurate documentation of laboratory work and presentation of results is required.
How You Will Achieve
Compliance with all Standard Operating Procedures (SOPs)
Complete all required trainings in compliance with departmental requirements and follow appropriate safety practices in the workplace
Plan, prioritize, and perform downstream processing of vaccine products and critical reagents
Protein A and Protein G purification of antibodies
Column packing of affinity columns
Perform in-process assays on vaccine products, process intermediates, and related experimental samples using biochemical/analytical tests
Collaborate with colleagues from partner groups in Vaccine Research and Development, including Bioprocess Fermentation, Analytical, and Formulation Development groups
Detailed, accurate, and timely documentation and review of experiments in a laboratory notebook
Qualifications
Must-Have
Prior experience with bioprocessing/purification
Experience running chromatography with AKTA systems using UNICORN software
Proficiency with personal computers including word processing, spreadsheets, PowerPoint and relevant scientific software is desirable
Strong verbal and written communication skills with attention to detail
Self-motivated and a positive attitude
Ability to learn new techniques, follow instructions, keep accurate records, and comply with SOPs
Proven ability to work independently in hands-on laboratory setting and collaborate as part of a team
Nice-to-Have
Knowledge and ability to independently execute purification/recovery activities
Proficiency in various techniques such as FPLC/HPLC, UV-Vis, and SDS-PAGE to isolate and/or characterize biomolecules
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.