The research lab headed by Dr. Deepika Vasudevan invites applications for a postdoctoral research fellow to work on mRNA translation regulation in retinal degeneration. The project will utilize Drosophila genetics, human cells and next-generation sequencing techniques to deduce how stress response pathways regulate development and disease states in the visual system. The project bears multiple publication opportunities, as well as open avenues for establishing independent research. The research has a broad impact, from advancing our understanding of how mRNA translation is regulated during stress to discovering therapeutic opportunities for treating age-related vision loss. 

The PI has a secondary appointment with the Department of Ophthalmology which provides diverse research resources and opportunities for collaboration and networking.

Responsibilities:  The successful candidate will lead the project intellectually, generate data, and utilize them to frame hypotheses. The incumbent will receive mentoring aligned with their career goals and is expected to develop a research program consistent with the goals of the lab and that of collaborators. Although the lab is well funded, s/he will be strongly encouraged to seek independent funding and participate in career development activities. The incumbent will also be expected to mentor students/junior lab members and train them in relevant protocols.

Qualifications:  The successful candidate should have a Ph.D. in the Biological sciences, should have demonstrated an academic record of excellence, and have effective communication skills. Their candidacy must be supported by confidential letters of recommendation from past mentors. Candidates who have led independent research projects using either Drosophila models or experience in vision research are preferred.

Salary range:  $56,484 - $68,604

Relevant publications:  1) A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oocyte maturation, and wing development. PMID: 34919148. 2) Translational induction of ATF4 mRNA during Integrated Stress Response requires eIF2D and DENR. PMID: 32938929.

Contact details:  

Deepika Vasudevan

Dept. of Cell Biology BST (South) S334

University of Pittsburgh

Ph: 631 827 2497

deepikav@pitt.edu

Lab website:  www.flystresslab.com

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