Job Description

Summary
The Section of Pediatric Surgery is looking for a Research Lab Specialist responsible for oversight of and technical contribution to vertebrate animal experiments and related scientific projects in a cancer biology research laboratory. Will function as a skilled specialist in all project(s) that involve murine models; and will contribute to molecular experiments, project coordination, grant and manuscript writing.

Responsibilities*
Perform and oversee in vivo tumorigenicity assays in murine models, subcutaneous, patient-derived xenograft models in immune deficient mice as well as genetic models in immune competent mice
Drug dosing, tumor, and toxicity monitoring in murine models
Genotyping and colony management
Small animal imaging IVIS, xRay, ultrasound
Necropsy & tissue dissection/fixation
Tissue preparation for molecular, biochemical and histologic studies
Monitor integrity of data collection and use of protocols and procedures
Write and collaborate with other researchers on manuscripts, abstracts, technical reports and other publications of research findings
Provide instruction and technical support to academic trainees in the lab
Direct day-to-day lab operations such as equipment maintenance and lab supply ordering
Coordinate the collection and analysis of data and the conduct of experimental procedures
Develop, design, and conduct more complex experiments in line with a research plan and review results periodically with faculty member or senior research staff member
Prepare, maintain and update IACUC protocols
Serve as lab liaison for IACUC- and ULAM-related inspections and regulatory reviews
Required Qualifications*
For Senior: Masters Degree and at least 5 years related experience
For Intermediate: Masters Degree and 4 years related experience
Excellent interpersonal and organizational skills
Must possess excellent written and oral communication skills
Demonstrated ability to teach and/or train students, junior laboratory personnel in laboratory techniques and/or protocols
Ability to work independently and as a member of our team
Excellent attendance, ability to multi-task, prioritize, and exercise good judgment is a must

Desired Qualifications*
Doctoral degree in Caner Biology or related field.
Demonstrated excellence and proven competency in establishing and monitoring murine tumor models
Proficiency with in vivo drug dosing and toxicity studies, blood collection, euthanasia, IP injections, and other standard murine-based procedures
Experience with mammalian cell culture, standard molecular/cellular biology techniques preferred
Ability to work with CRISPR and Cre-Lox models.
Familiarity with University research administration, policies and procedures - especially those related to IACUC and ULAM
Underfill Statement
This position is posted at the Research Lab Specialist Senior classification; however, it may be underfilled at a lower classification (Research Lab Specialist Intermediate) depending on the qualifications of the candidate.