Research Associate I

The Jaeger Lab in the Department of Molecular Oncology at Moffitt Cancer Center is seeking motivated candidate for a Research Associate position. This position will integrate molecular oncology and tumor immunology in a highly multidisciplinary research program. The Jaeger Lab uses sophisticated mouse models, cutting edge mass spectrometry, next generation sequencing, patient derived organoids and clinical specimens to identify and characterize patterns of antigen presentation in the tumor microenvironment. Research Associates in the Jaeger Lab will receive active mentorship and rigorous scientific training that will support young scientists to achieve their career goals including entrance into graduate or medical school.

Following up on our previous work (https://www.nature.com/articles/s41586-022-04839-2), we have developed novel mouse strains that enable precise interrogation of protein synthesis and antigen presentation from cancer cells in vivo. Using these mouse strains, the lab will explore the fundamental relationships between gene expression, protein translation, and antigen presentation throughout tumor evolution. In parallel, the Jaeger Lab uses human cells and clinical samples to explore opportunities to translate our findings in mouse models to the clinical setting. Insights gained from these experiments will provide a blueprint for designing novel immunotherapies including cancer vaccines, tumor targeting antibodies, and adoptive cell therapies. Research in the lab incorporates both fundamental basic science and translational cancer research and lab members are expected be fully engaged with all aspects of the lab including experiments, lab operations, and maintaining a healthy, collaborative, and fun lab culture.

Position Highlights:

• The Research Associate I will be responsible for executing experiments to support the active research programs in the Jaeger Lab. 
• Work with cutting-edge mass spectrometry, next-generation sequencing, and imaging techniques.
• Dynamic, interdisciplinary, and collegial environment with numerous basic and translational collaborations.
• Highly engaged mentorship to ensure effective training and scientific growth.
• Ample opportunity to contribute to publications.
• Position is in a new lab with high growth potential and increased responsibility over time.
• Unique access to clinical samples and interactions with clinicians at the cutting edge of cancer treatment.

Ideal Candidate: 

• Ability to plan, organize and coordinate work assignments.
• Eager to learn techniques related to mass spectrometry, protein purification, multiplexed imaging, next generation sequencing library preparation, and immunology.
• Ability to establish and maintain effective working relationships with others and communicate clearly, verbally and in writing.

Responsibilities:

• Performs experiments under the supervision of Dr. Jaeger.
• Assists in maintaining mouse colony breeding and record keeping.
• Technically responsible for the collection, organization and permanent documentation of data in physical and electronic formats.
• Coordinate general lab activities including inventory record keeping, maintenance of safety protocols, and equipment maintenance.

Credentials and Qualifications:

• Bachelor’s Degree is required.
• Excellent verbal and written communication skills are required.
• Candidates with hands on wet-lab research experience will be strongly considered.